Nephrology

Renal Transplantation & Multiple Organ Transplantation

Renal Transplantation is the method of treatment where the person in the End Stage Renal Disease. Generally the initial stages of the disease can be treated and transplantation is done only in the final stage of kidney disease where the kidney cannot perform its function further. In this method the affected person is treated with the replacement of healthy kidney. Deceased Donor transplantation is the method where the kidney is transplanted from the died person. In most cases the died individuals are strangers who wants to donate the kidney. Transplantation can also be done through living ones which could be genetically related person & different person. While dealing with the immunology, there might the chance of rejection due to incompatibility. Therefore the donor and recipient should be in the ABO blood group and cross match Human Leucocyte Antigen (HLA) compatible. If a potential living donor is contrary with his/her recipient, the donor could be traded for a good kidney. To reduce the rejection rate during incompatible transplantation, ABO & HLA antibodies are reduced which recipient may have for the donor through desensitization procedure using intravenous immunoglobulin (IVIg).